Article
The vacuolar H(+)-ATPase of Saccharomyces cerevisiae is required for efficient copper detoxification, mitochondrial function, and iron metabolism.
Molecular & general genetics : MGG - 1 Nov 1993
Eide D J, Bridgham J T, Zhao Z, Mattoon J R
Abstract excerpt
Mutations in the GEF2 gene of the yeast Saccharomyces cerevisiae have pleiotropic effects. The gef2 mutants display a petite phenotype. These cells grow slowly on several different carbon sources utilized exclusively or primarily by respiration. This phenotype is suppressed by adding large amount...
Topics
- Base Sequence
- Cations, Divalent
- Copper
- DNA, Fungal
- Genes, Fungal
- Iron
- Mitochondria
- Molecular Sequence Data
- Mutation
- Proton-Translocating ATPases
- Restriction Mapping
- Saccharomyces cerevisiae
- Vacuoles