The amiloride resistance gene, car1, of Schizosaccharomyces pombe.

doi:10.1007/BF00284681

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Article

The amiloride resistance gene, car1, of Schizosaccharomyces pombe.

Molecular & general genetics : MGG - 1 Nov 1993

Jia Z P, McCullough N, Wong L, Young P G

Abstract excerpt

Amiloride, an inhibitor of various sodium transporters, is toxic to Schizosaccharomyces pombe at low concentration in minimal but not in rich media. Amiloride-resistant mutants were isolated and shown to represent a new locus (car1 for changed amiloride resistance) on chromosome I. The car1 gene was cloned and sequenced. Sequence analysis revealed an open reading frame of 526 amino acids with a predicted...

Topics

Alleles
Amiloride
Amino Acid Sequence
Arginase
Cloning, Molecular
Drug Resistance, Microbial
Fungal Proteins
Genes, Fungal
Membrane Proteins
Membrane Transport Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Restriction Mapping

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Homology, Amino Acid

Sodium

Source

Open in PubMed

Identifiers

PMID: 8246883
DOI: 10.1007/BF00284681

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8246883-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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