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Article

CZT-1 is a novel transcription factor controlling cell death and natural drug resistance in Neurospora crassa.

G3 (Bethesda, Md.) - 8 Apr 2014

Gonçalves A Pedro, Hall Charles, Kowbel David J, Glass N Louise, Videira Arnaldo

Abstract excerpt

We pinpoint CZT-1 (cell death-activated zinc cluster transcription factor) as a novel transcription factor involved in tolerance to cell death induced by the protein kinase inhibitor staurosporine in Neurospora crassa. Transcriptional profiling of staurosporine-treated wild-type cells by RNA-sequencing showed that genes encoding the machinery for protein synthesis are enriched among the genes repressed by the...

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Identifiers

PMID: 24717808
DOI: 10.1534/g3.114.011312
PMCID: PMC4065252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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