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Article

Dissociation of the tetrameric phosphoglycerate mutase from yeast by a mutation in the subunit contact region.

The Biochemical journal - 1 Nov 1993

White M F, Fothergill-Gilmore L A, Kelly S M, Price N C

Abstract excerpt

Phosphoglycerate mutases from different sources exhibit a variety of quaternary structures (tetramer, dimer and monomer). To perturb the tetrameric structure of yeast phosphoglycerate mutase we have prepared a mutant enzyme in which Lys-168 in the subunit-contact region has been replaced by proline. The K168P mutant enzyme undergoes dissociation to dimers at low concentrations; thus on lowering the concentration...

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Identifiers

PMID: 8240286
DOI: 10.1042/bj2950743
PMCID: PMC1134623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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