Article
Glu327 is part of a catalytic triad in rat liver fructose-2,6-bisphosphatase.
The Journal of biological chemistry - 5 Apr 1992
Lin K, Li L, Correia J J, Pilkis S J
Abstract excerpt
The fructose-2,6-bisphosphatase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase has been shown to be structurally and functionally homologous to phosphoglycerate mutase. Both enzymes catalyze their reactions via phosphoenzyme intermediates which utilize an active site histidine as a nucleophilic phosphoacceptor and another histidine as a proton donor to the leaving group. Glu327 in the...
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