The Detection of Aspergillus spp. by the Polymerase Chain Reaction and Its Evaluation in Bronchoalveolar Lavage Fluid

Abstract excerpt

Invasive pulmonary aspergillosis (IPA) is an important cause of mortality and morbidity in the immunocompromised host. However, the diagnosis of this condition may be difficult, and it is sometimes missed because of the lack of sensitivity of available tests. Therefore, we used polymerase chain reaction (PCR)-based amplification of fragments of genes-encoding alkaline proteases from Aspergillus fumigatus and A....

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