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Polymerase Chain Reaction Detection ofAspergillusDNA in Experimental Models of Invasive Aspergillosis

15 Apr 2002

Abstract excerpt

To determine the sensitivity of polymerase chain reaction (PCR) assays for the diagnosis of invasive aspergillosis, results of quantitative culture, PCR-ELISA, and a quantitative LightCycler assay (Roche Diagnostics) of blood and organ specimens of experimentally infected mice and rabbits were compared. By PCR-ELISA, 297 of 379 murine lung specimens were positive, but only 235 of 379 were culture positive....

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PMID: 11930335
DOI: 10.1086/339824

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