Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar lavage fluid

29 May 2008

Abstract excerpt

BACKGROUND: The diagnosis of invasive pulmonary aspergillosis (IPA) remains challenging. Culture and histopathological examination of bronchoalveolar lavage (BAL) fluid are useful but have suboptimal sensitivity and in the case of culture may require several days for fungal growth to be evident. Detection of Aspergillus DNA in BAL fluid by quantitative PCR (qPCR) offers the potential for earlier diagnosis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Infectious Diseases and Mycology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18510764
DOI: 10.1186/1471-2334-8-73

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development and optimization of quantitative PCR for the diagnosis of invasive aspergillosis with bronchoalveolar lavage fluidPMID 18510764Read ↗

PCR-based diagnosis of human fungal infectionsSemantic proximity Read ↗

Molecular Detection and Species-Specific Identification of Medically Important Aspergillus Species by Real-Time PCR in Experimental Invasive Pulmonary AspergillosisSemantic proximity Read ↗

Detection of Aspergillus flavus and A. fumigatus in Bronchoalveolar Lavage Samples of Hematopoietic Stem Cell Transplants and Patients with Hematological Malignancies by Real-Time Polymerase Chain Reaction, Nested Polymerase Chain Reaction and Mycological AssaysSemantic proximity Read ↗

Determining the analytical specificity of PCR-based assays for the diagnosis of IA: What isAspergillus?Semantic proximity Read ↗

Establishment and application of real-time quantitative PCR for diagnosing invasive Aspergillosis via the blood in hematological patients: targeting a specific sequence of Aspergillus 28S-ITS2Semantic proximity Read ↗

Diagnostic Value of Microbial Cell-free DNA Sequencing for Suspected Invasive Fungal Infections: A Retrospective Multicenter Cohort StudySemantic proximity Read ↗

A MIQE-Compliant Real-Time PCR Assay for Aspergillus DetectionSemantic proximity Read ↗

Detection of Aspergillus fumigatus in a Rat Model of Invasive Pulmonary Aspergillosis by Real-Time Nucleic Acid Sequence-Based AmplificationSemantic proximity Read ↗

Detection of Aspergillus fumigatus by polymerase chain reactionSemantic proximity Read ↗

Bacterial quantification assay to detect and monitor <i>Pseudomonas aeruginosa</i> infection in patients with bronchiectasisSemantic proximity Read ↗

Quantitative real time PCR for distinction between Pneumocystis jirovecii infection/colonization in hospitalized patientsSemantic proximity Read ↗

Specific Detection of Aspergillus Species in Blood and Bronchoalveolar Lavage Samples of Immunocompromised Patients by Two-Step PCRSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.