Article
[Linkage analysis in pedigrees with Alzheimer's dementia].
Vnitrni lekarstvi - 1 Oct 1993
Mazura I, Jirák R, Koukolík F
Abstract excerpt
Linkage analysis with three specific DNA markers was carried out on the Alzheimer's dementia pedigrees. The DNA markers used in our study, D21S1/D21S11, D21S13 and D21S16 in the 21q11.2-21q21 regions are localized. The results from different brain DNA samples and from peripheral blood samples of AD families were evaluated by two-point linkage analysis. The linkage between DNA markers and one AD pedigree was...
Topics
- Alleles
- Alzheimer Disease
- Genetic Linkage
- Genetic Markers
- Humans
- Pedigree