Article
[Collection of a Chinese pedigree with Parkinson's disease and linkage analysis of nine susceptibility genes].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Jun 2006
Sun Hao, Zhang Chang-Jun, Shu Qing, Tian You-Yong, Shi Lei, Yu Jian-Kun, Qian Ya-Ping, Chu Jia-You
Abstract excerpt
OBJECTIVE: To analyze the susceptibility genes of a Parkinson's Disease (PD) family. METHODS: The blood samples of a four-generation classic idiopathic PD family were collected. Two-point LOD score method was applied to analyze the linkage disequilibrium between the disease locus and microsatellite markers. RESULTS: We studied 13 markers near the 9 genes that had been reported to be associated with PD. No obvious...
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