Article
Genetic-based differences in neurotensin levels and receptors in brains of LS x SS mice.
Peptides - 1 Jan 2000
Erwin V G, Radcliffe R, Hinkle B, Jones B C
Abstract excerpt
Levels of endogenous neurotensin (NT-IR) in the LS x SS RI strains differed by 3.0-, 4.7-, 5.4-, and 6.9-fold in the ventral midbrain (VMB), hypothalamus (HY), nucleus accumbens (NA), and caudate putamen (CP), respectively. Frequency distributions and estimates of the number of genes indicate that differences in NT-IR are polygenically influenced. The NT-IR levels in NA and CP were significantly correlated, but...
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