Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system.

doi:10.1016/s0014-5793(96)01391-9

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Article

Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system.

FEBS letters - 3 Jan 1997

Botto J M, Sarret P, Vincent J P, Mazella J

Abstract excerpt

This work describes the molecular cloning of a variant isoform of the low-affinity levocabastine-sensitive neurotensin receptor isolated from mouse brain. Although the corresponding mRNA encodes for a 282 amino acid protein unable to bind neurotensin after transient transfection in COS-7 cells, this non-functional neurotensin receptor is expressed in cerebral neocortex, cerebellum, olfactory bulb, striatum and...

Topics

Amino Acid Sequence
Animals
Base Sequence
Brain
COS Cells
Cloning, Molecular
DNA, Complementary
Gene Expression
Genetic Variation
Mice
Molecular Sequence Data
Neurotensin
Piperidines
Receptors, Neurotensin

Source

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Identifiers

PMID: 9001400
DOI: 10.1016/s0014-5793(96)01391-9

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