Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons.

Journal of virology - 1 Dec 1993

de la Torre J C, Rall G, Oldstone C, Sanna P P, Borrow P, Oldstone M B

Abstract excerpt

We have investigated the replication of lymphocytic choriomeningitis virus (LCMV) before and after the nerve growth factor (NGF)-induced transdifferentiation of PC12 cells from the chromaffin to the neuron-like phenotype. Untreated and NGF-treated cells were equally susceptible to LCMV infection; however, the viral yield was found to be 1,000-fold lower in NGF-differentiated PC12 cells. The reduced viral yield...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Division
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Nerve Growth Factors

Share to Neurons

Share to Selection, Genetic

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 8230458
DOI: 10.1128/JVI.67.12.7350-7359.1993
PMCID: PMC238199

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons.PMID 8230458Read ↗

Borna Disease Virus Persistent Infection Activates Mitogen-activated Protein Kinase and Blocks Neuronal Differentiation of PC12 CellsSemantic proximity Read ↗

Characterization of an In Vitro Model of Alphavirus Infection of Immature and Mature NeuronsSemantic proximity Read ↗

Herpes simplex virus type 1 infection prevents detachment of nerve growth factor-differentiated PC12 cells in culture.Semantic proximity Read ↗

Differentiated Neuroblastoma Cells Provide a Highly Efficient Model for Studies of Productive Varicella-Zoster Virus Infection of Neuronal CellsSemantic proximity Read ↗

ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal CellsSemantic proximity Read ↗

HIV-1 gene expression and replication in neuronal and glial cell lines with immature phenotype: effects of nerve growth factor.Semantic proximity Read ↗

Long-term productive human cytomegalovirus infection of a human neuroblastoma cell lineSemantic proximity Read ↗

Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencingSemantic proximity Read ↗

Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone depositionSemantic proximity Read ↗

Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone depositionSemantic proximity Read ↗

Analysis of a multi-mutant herpes simplex virus type 1 for gene transfer into sympathetic preganglionic neurons and a comparison to adenovirus vectors.Semantic proximity Read ↗

Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.