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Article

Viral microRNA effects on persistent infection of human lymphoid cells by polyomavirus SV40.

PloS one - 1 Jan 2018

McNees Adrienne L, Harrigal Lindsay J, Kelly Aoife, Minard Charles G, Wong Connie, Butel Janet S

Abstract excerpt

BACKGROUND: Polyomaviruses, including simian virus 40 (SV40), display evidence of lymphotropic properties. This study analyzed the nature of SV40-human lymphocyte interactions in established cell lines and in primary lymphocytes. The effects of viral microRNA and the structure of the viral regulatory region on SV40 persistence were examined. RESULTS: SV40 DNA was maintained in infected B cell and myeloid cell...

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Share to Antigens, Polyomavirus Transforming
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Viral

Share to Host-Pathogen Interactions

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Share to Regulatory Sequences, Ribonucleic Acid

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Source

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Identifiers

PMID: 29432481
DOI: 10.1371/journal.pone.0192799
PMCID: PMC5809058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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