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Article

Cell-type-specific control elements of the lymphotropic papovavirus enhancer.

Journal of virology - 1 Apr 1990

Erselius J R, Jostes B, Hatzopoulos A K, Mosthaf L, Gruss P

Abstract excerpt

Lymphotropic papovavirus (LPV) exhibits a highly restricted host range, in which only cells of primate B-lymphocyte origin are permissive for infection. Its enhancer element contributes to this tropism, since transcriptional potentiation is confined to cells of the hematopoietic lineage. Nuclear extracts from B and T cells, but not from HeLa cells, contain protein factors that interact specifically with the LPV...

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Identifiers

PMID: 2319649
DOI: 10.1128/JVI.64.4.1657-1666.1990
PMCID: PMC249302

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