Article
1H NMR study of the dynamics of the pH modulation of axial coordination in Aplysia limacina (Val(E7)) and sperm whale double mutant His(E7)-->Val,Thr(E10)-->Arg metmyoglobin.
The Journal of biological chemistry - 15 Nov 1993
Qin J, Pande U, La Mar G N, Ascoli F, Ascenzi P, Cutruzzolá F, Travaglini-Allocatelli C, Brunori M
Abstract excerpt
The molecular and electronic structure, thermodynamics, dynamics, and mechanism of interconversion of the pH-modulated reversible equilibria of Aplysia limacina metmyoglobin, (metMb), have been investigated by 1H NMR spectroscopy. The four identified species which interconvert slowly on the NMR t...
Topics
- Amino Acids
- Animals
- Aplysia
- Hydrogen Bonding
- Hydrogen-Ion Concentration
- Magnetic Resonance Spectroscopy
- Metmyoglobin
- Mutation
- Protein Conformation
- Protons
- Whales