Article
<i>Legionella pneumophila</i> Utilizes the Same Genes To Multiply within <i>Acanthamoeba castellanii</i> and Human Macrophages
1 May 1999
Abstract excerpt
In previous reports we described a 22-kb Legionella pneumophila chromosomal locus containing 18 genes. Thirteen of these genes (icmT, -R, -Q, -P, -O, -M, -L, -K, -E, -C, -D, -J, and -B) were found to be completely required for intracellular growth and killing of human macrophages. Three genes (icmS, -G, and -F) were found to be partially required, and two genes (lphA and tphA) were found to be dispensable for...
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