Article
The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation.
Cell - 6 Mar 1992
Gao W Q, Liu X L, Hatten M E
Abstract excerpt
In the neurological mutant mouse weaver, CNS precursor cells in the external germinal layer (EGL) of the cerebellar cortex proliferate normally, but fail to differentiate and die in the proliferative zone. To examine the autonomy of expression of the weaver gene, we carried out cell-mixing experiments in vitro. In homotypic, reaggregate cultures, weaver EGL precursor cells expressed the general neuronal markers...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.