Article
The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation.
Cell - 6 Mar 1992
Gao W Q, Liu X L, Hatten M E
Abstract excerpt
In the neurological mutant mouse weaver, CNS precursor cells in the external germinal layer (EGL) of the cerebellar cortex proliferate normally, but fail to differentiate and die in the proliferative zone. To examine the autonomy of expression of the weaver gene, we carried out cell-mixing experi...
Topics
- Animals
- Cell Adhesion Molecules, Neuronal
- Cell Communication
- Cell Differentiation
- Cells, Cultured
- Cerebellar Cortex
- Contactin 2
- Glycoproteins
- In Vitro Techniques
- Membrane Glycoproteins
- Mice
- Mice, Mutant Strains
- Microtubule-Associated Proteins
- Nerve Tissue Proteins
- Neurites
- Phenotype
- Rats
- Signal Transduction