Sequence of an exon of the feline p53 gene--mutation in a lymphosarcoma.

doi:10.1016/S0007-1935(05)80077-6

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Article

Sequence of an exon of the feline p53 gene--mutation in a lymphosarcoma.

The British veterinary journal - 1 Jan 2000

Mayr B, Heczko U, Schellander K, Schleger W, Reifinger M

Abstract excerpt

Exon 8 of tumour suppressor gene p53 was sequenced in domestic cats and showed remarkable similarity to the human sequence. Only four of the 13 nucleotide differences gave rise to interspecific amino acid differences. In an investigated lymphosarcoma we detected a mutation cgg --> tgg (arginine -...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cat Diseases
Cats
Codon
Exons
Genes, p53
Humans
Lymphoma, Non-Hodgkin
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Sequence Homology, Amino Acid

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