Article
Sequence of an exon of tumour suppressor p53 gene--a comparative study in domestic animals: mutation in a feline solid mammary carcinoma.
The British veterinary journal - 1 Jan 2000
Mayr B, Schaffner G, Kurzbauer R, Reifinger M, Schellander K
Abstract excerpt
Partial sequence determinations were performed on exon 8 of tumour suppressor gene p53 of cattle, sheep, goat, horse and pig. High sequence homology between these species and other species including dog, cat, chicken and man is demonstrated. A mutation CGG-->TGG (arginine-->tryptophan) was detected in a feline solid carcinoma of the mammary gland.
Topics
- Animals
- Animals, Domestic
- Base Sequence
- Cat Diseases
- Cats
- DNA Primers
- DNA, Neoplasm
- Exons
- Genes, p53
- Humans
- Mammary Neoplasms, Animal
- Molecular Sequence Data
