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Article

Response of Plasmodium vivax variants to chloroquine as determined by microscopy and quantitative polymerase chain reaction.

The American journal of tropical medicine and hygiene - 1 Oct 1993

Kain K C, Brown A E, Lanar D E, Ballou W R, Webster H K

Abstract excerpt

Genotypic heterogeneity in the repetitive portion of the circumsporozoite (CS) protein of Plasmodium vivax has been reported from many P. vivax-endemic areas. The objective of this study was to determine if the VK210 and VK247 CS variants of P. vivax differed in their clearance rates following chloroquine (CQ) therapy. One hundred seventy-one cases of P. vivax infection occurring in patients presenting to a...

Topics

Adult
Animals
Base Sequence
Chloroquine
DNA Primers
DNA, Protozoan
Genotype
Humans
Malaria, Vivax
Male
Molecular Sequence Data
Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmodium vivax

Polymerase Chain Reaction

Protozoan Proteins

Source

Identifiers

PMID: 8214278
DOI: 10.4269/ajtmh.1993.49.478

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8214278-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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