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Article

Genetic signatures of Plasmodium vivax Circumsporozoite Surface Protein during malaria resurgence in Thailand.

International journal for parasitology - 1 Jun 2026

Tapaopong Parsakorn, Holzschuh Aurel, da Silva Gustavo, Chintanawiwat Palakorn, Bantuchai Sirasate, Rungsarityotin Wasinee, Cui Liwang, Koepfli Cristian, Sattabongkot Jetsumon, Nguitragool Wang

Abstract excerpt

The Plasmodium circumsporozoite surface protein (CSP) is the best characterized pre-erythrocytic vaccine target for malaria. It is a multifunctional protein important for sporozoite mobility, mosquito salivary gland invasion, and hepatocyte invasion. We analyzed diversity of Plasmodium vivax CSP gene (pvcsp) during the 2022-2023 malaria resurgence in northwestern Thailand and assessed how pvcsp haplotypes may...

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Identifiers

PMID: 41380756
DOI: 10.1016/j.ijpara.2025.12.001
PMCID: PMC12949852

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