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Phenotype and genotype diversity in the circumsporozoite proteins of Plasmodium vivax in Thailand.

Molecular and biochemical parasitology - 1 Nov 1995

Rongnoparut P, Supsamran N, Sattabongkot J, Suwanabun N, Rosenberg R

Abstract excerpt

Two phenotypes of the circumsporozoite (CS) protein of the human malaria parasite Plasmodium vivax occur in Thailand, each of which has a characteristic nonamer repeat: GDRA(A/D)GQPA for VK210-type and ANGAG-NQPG for VK247-type. We have sequenced the repetitive domains and flanking regions from 17 specimens collected from a small area, some of which had given ambiguous results in allele-specific hybridization or...

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PMID: 8719161
DOI: 10.1016/0166-6851(95)02504-9

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