Article
Detection of the hepatitis B virus major pre-core mutation by the amplification refractory mutation system technique.
Research in virology - 1 Jan 2000
Gramegna M, Lampertico P, Lobbiani A, Colucci G
Abstract excerpt
HBeAg/anti-HBe seroconversion is associated, in some patients affected by type B chronic active hepatitis (CAH), with the occurrence of HBV pre-core mutants characterized by a common G-A change at codon 83. Since this mutation has important clinical correlations, we tried to develop a fast and reliable PCR test based on the amplification refractory mutation system (ARMS) technique, which has been successfully...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.