Article
Environmental induction of tumor phenotype in a putative Kaposi sarcoma progenitor cell.
Lymphology - 1 Mar 1994
Mallery S R, Lantry L E, Hegtvedt A, Lazo A, Titterington L C, Hout B L, Brierley G P, Stephens R E
Abstract excerpt
Many features of AIDS-related Kaposi sarcoma (AIDS-KS), e.g., multifocal lesional presentation at sites perfused by the microvasculature, suggest that AIDS-KS is initially a hyperplasia that subsequently progresses to a neoplasia. We propose that the unique AIDS environment, which contains high l...
Topics
- AIDS-Related Complex
- Cell Differentiation
- Cell Transformation, Neoplastic
- Endothelium, Vascular
- Humans
- Phenotype
- Sarcoma, Kaposi
- Stem Cells
- Tumor Cells, Cultured