Article

Single-cell RNA sequencing identifies KSHV-infected Mesenchymal stem cell subpopulations precursors of Kaposi’s Sarcoma

2023-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Kaposi’s sarcoma (KS) may derive from Kaposi’s Sarcoma Herpesvirus (KSHV)-infected human Mesenchymal Stem Cells (hMSCs) migrating into an inflammatory and angiogenic site, enhancing KS initiation. KSHV infection of primary hMSCs uncovers specific cell subpopulations, mechanisms, and conditions involved in the first steps of the KSHV-induced transformation and reprogramming process toward KS prog...

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Literature Corpus work: e6eab5f9-08b9-50d3-8631-8243f2c7d236
DOI: 10.1101/2023.02.28.530387

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