Article
Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.
Cell - 3 Jun 1994
Gee S H, Montanaro F, Lindenbaum M H, Carbonetto S
Abstract excerpt
Aggregation of acetylcholine receptors (AChRs) on skeletal muscle fibers is thought to be mediated by the basal lamina protein agrin. Structural similarities shared by agrin and laminin suggested that the laminin receptor dystroglycan-alpha, part of a dystrophin-receptor complex, might also bind agrin. We show here that dystroglycan-alpha and dystrophin-related protein (DRP/utrophin) are concentrated within AChR...
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