Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.

doi:10.1016/0092-8674(94)90052-3

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Article

Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.

Cell - 3 Jun 1994

Gee S H, Montanaro F, Lindenbaum M H, Carbonetto S

Abstract excerpt

Aggregation of acetylcholine receptors (AChRs) on skeletal muscle fibers is thought to be mediated by the basal lamina protein agrin. Structural similarities shared by agrin and laminin suggested that the laminin receptor dystroglycan-alpha, part of a dystrophin-receptor complex, might also bind...

Topics

Agrin
Animals
Antibodies, Monoclonal
Cells, Cultured
Cytoskeletal Proteins
Dystroglycans
Dystrophin
Laminin
Membrane Glycoproteins
Muscles
Mutation
Receptor Aggregation
Receptors, Growth Factor

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