Article
Immunohistochemical characterization of a monoclonal antibody to hyperplastic nodules induced in rat liver by chemical carcinogens.
Journal of gastroenterology - 1 Feb 1994
Kurokawa F
Abstract excerpt
To investigate the specific phenotype of hyperplastic nodules (HPN) in rat liver, we produced a monoclonal antibody (HAM-6). HAM-6 was a member of the mouse IgG1 class and was specific for hyperplastic nodules, as shown by cellular radioimmunoassay and immunohistochemical studies. The antigen rec...
Topics
- 2-Acetylaminofluorene
- Animals
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Carcinoma, Hepatocellular
- Diethylnitrosamine
- Hyperplasia
- Immunohistochemistry
- Liver
- Liver Neoplasms
- Male
- Mice
- Mice, Inbred BALB C
- Phenotype
- Precancerous Conditions
- Radioimmunoassay
- Rats
- Rats, Inbred F344