Article
Genotypic differentiation of intrahepatically transplanted hyperplastic nodule cells of analbuminemic and normal rat origin by polymerase chain reaction.
Japanese journal of cancer research : Gann - 1 Aug 1990
Nishikawa Y, Sakai H, Inagaki M, Fukuda I, Ogawa K, Nagase S
Abstract excerpt
DNA fragments encompassing the region of the seven-base-pair deletion in the albumin gene, which is a characteristic abnormality of Nagase's analbuminemic rat (NAR), were amplified by polymerase chain reaction, and we could differentiate the genotypes of normal rat, homozygous NAR and heterozygous NAR electrophoretically. This genotyping method was applied to the differentiation of hyperplastic nodules on...
Topics
- Albumins
- Animals
- Base Sequence
- Chromosome Deletion
- Genotype
- Heterozygote
- Homozygote
- Hyperplasia
- Liver
- Molecular Sequence Data
- Polymerase Chain Reaction