Article
Effect of genetically determined host factors on the efficacy of vidarabine, acyclovir and 5-trifluorothymidine in herpes simplex virus type 1 infection.
Ophthalmic research - 1 Jan 1994
Abghari S Z, Stulting R D, Zhu Z, Schinazi R F, Kaufman H E
Abstract excerpt
The susceptibility of Herpes simplex virus (HSV) to acyclovir (ACV), 5-trifluorothymidine (TFT) and vidarabine (Ara-A) in HSV-infected embryo fibroblasts from BALB/c and C57BL/6 mice as well as Vero cells were measured. Ara-A and TFT (at its highest concentration) were more effective in Vero cell...
Topics
- Acyclovir
- Animals
- Embryo, Mammalian
- Female
- Fibroblasts
- Genetic Variation
- Herpesvirus 1, Human
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Pregnancy
- Trifluridine
- Vero Cells
- Vidarabine
- Virus Replication