Mutagenesis of Legionella pneumophila using Tn903 dlllacZ: identification of a growth-phase-regulated pigmentation gene.

doi:10.1111/j.1365-2958.1994.tb00343.x

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Article

Mutagenesis of Legionella pneumophila using Tn903 dlllacZ: identification of a growth-phase-regulated pigmentation gene.

Molecular microbiology - 1 Feb 1994

Wiater L A, Sadosky A B, Shuman H A

Abstract excerpt

Study of the molecular basis for Legionella pneumophila pathogenicity would be facilitated with an efficient mutagen that can not only mark genomic mutations, but can also be used to reflect gene expression during macrophage infection. A derivative of Tn903, Tn903dlllacZ, is shown to transpose wi...

Topics

Alleles
DNA Transposable Elements
Genes, Bacterial
Humans
Legionella pneumophila
Monocytes
Mutagenesis, Insertional
Phenotype
Pigments, Biological
Recombinant Fusion Proteins
Tumor Cells, Cultured

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