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Article

Large-scale transposon mutagenesis of Mycoplasma pulmonis.

Molecular microbiology - 1 Jul 2008

French Christopher T, Lao Ping, Loraine Ann E, Matthews Brian T, Yu Huilan, Dybvig Kevin

Abstract excerpt

To obtain mutants for the study of the basic biology and pathogenic mechanisms of mycoplasmas, the insertion site of transposon Tn4001T was determined for 1700 members of a library of Mycoplasma pulmonis mutants. After evaluating several criteria for gene disruption, we concluded that 321 of the 782 protein coding regions were inactivated. The dispensable and essential genes of M. pulmonis were compared with...

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Identifiers

PMID: 18452587
DOI: 10.1111/j.1365-2958.2008.06262.x
PMCID: PMC2453687

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Source receipt: pubmed, retrieved 7 Sept 2026.

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