In vitro construction of graded thymus chimeras.

doi:10.1016/0022-1759(94)90038-8

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Article

In vitro construction of graded thymus chimeras.

Journal of immunological methods - 16 May 1994

Merkenschlager M, Fisher A G

Abstract excerpt

A simple in vitro approach is described for constructing chimeric thymi in which the degree of chimeric contribution can be tightly controlled. This is achieved by protease-assisted dissociation of fresh fetal thymic tissue, mixing the resulting cell suspensions at the desired ratios, and subsequ...

Topics

Animals
Chimera
Hematopoietic Stem Cells
In Vitro Techniques
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Phenotype
Stromal Cells
T-Lymphocytes
Thymus Gland

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