Structure of the human Na+/glucose cotransporter gene SGLT1.

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Article

Structure of the human Na+/glucose cotransporter gene SGLT1.

The Journal of biological chemistry - 27 May 1994

Turk E, Martín M G, Wright E M

Abstract excerpt

Intestinal uptake of dietary glucose and galactose is mediated by the SGLT1 Na+/glucose cotransporter of the brush border. An SGLT1 missense mutation underlies hereditary glucose/galactose malabsorption, characterized by potentially fatal diarrhea; conversely, oral rehydration therapy exploits normal transport to alleviate life-threatening diarrhea of infectious origin. We have mapped the entire human SGLT1...

Topics

Amino Acid Sequence
Base Sequence
Carrier Proteins
Child, Preschool
Cloning, Molecular
DNA
Exons
Galactose
Glucose
Humans
Introns
Malabsorption Syndromes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Membrane Glycoproteins

Membrane Proteins

Molecular Sequence Data

Monosaccharide Transport Proteins

Mutation

Source

Open in PubMed

Identifiers

PMID: 8195156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8195156-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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