Article
Assignment of the human Na+/glucose cotransporter gene SGLT1 to chromosome 22q13.1.
Genomics - 1 Sept 1993
Turk E, Klisak I, Bacallao R, Sparkes R S, Wright E M
Abstract excerpt
The Na+/glucose cotransporter gene SGLT1 encodes the primary carrier protein responsible for the uptake of the dietary sugars glucose and galactose from the intestinal lumen. SGLT1 transport activity is currently exploited in oral rehydration therapy. The 75-kDa glycoprotein is localized in the brush border of the intestinal epithelium and is predicted to comprise 12 membrane spans. In two patients with the...
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