Article
Molecular basis for glucose-galactose malabsorption.
Cell biochemistry and biophysics - 1 Jan 2002
Wright Ernest M, Turk Eric, Martin Martin G
Abstract excerpt
Glucose-galactose malabsorption (GGM) is an autosomal recessive disease that presents in newborn infants as a life-threatening diarrhea. The diarrhea ceases within 1 h of removing oral intake of lactose, glucose, and galactose, but promptly returns with the introduction of one or more of the offending sugars into the diet. Our goal is to determine whether or not mutations in the sodium-glucose cotransporter gene...
Topics
- Carbohydrate Metabolism, Inborn Errors
- Chromosomes, Human, Pair 22
- Female
- Galactose
- Glucose
- Humans
- Infant, Newborn
- Intestinal Absorption
- Malabsorption Syndromes
- Male
- Membrane Glycoproteins
- Monosaccharide Transport Proteins
- Mutation
- Sodium-Glucose Transporter 1