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Article

Antigenic surface of the bee venom allergen phospholipase A2. Structural functional analysis of human IgG4 antibodies reveals potential role in protection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1994

Dudler T, Schneider T, Annand R R, Gelb M H, Suter M

Abstract excerpt

In the human immune response to the main bee venom allergen phospholipase A2 (PLA2), Abs of the IgG4 isotype are associated with protection. The antigenic sites of PLA2 that are recognized by two mAb of this isotype have been analyzed at the molecular level. The interaction of PLA2 with these two...

Topics

Allergens
Antibodies, Monoclonal
Base Sequence
Bee Venoms
Enzyme-Linked Immunosorbent Assay
Humans
Immunoglobulin G
Molecular Sequence Data
Mutation
Phospholipases A
Phospholipases A2

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PMID: 8189069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8189069-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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