[Mutational level of translocated variants of Down's syndrome in Leningrad (1982-1991)].

Article

[Mutational level of translocated variants of Down's syndrome in Leningrad (1982-1991)].

Genetika - 1 Mar 1994

Kovaleva N V, Butomo I V, Verlinskaia D K, Mant D I, Pavlova M N, Pantova I G, Prozorova M V, Shandlorenko S K, Shmatova I A

Abstract excerpt

Karyological study of 644 newborns with Down's syndrome (DS) revealed 37 translocation cases (5.7%). Translocations were inherited in 8 cases, in 17 cases they were sporadic, and in 12 cases parents were not examined. Total mutation rate per gamete per generation (2.7.10) and mutation rates of D/...

Topics

Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 21
Down Syndrome
Female
Humans
Infant, Newborn
Male
Mutation
Russia
Translocation, Genetic

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