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[Association of MTHFR and MTRR genes polymorphisms with non-disjunctions of chromosomes 18 and 21].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2015

Guo Qiannan, Wang Hongdan, Yang Ke, Zhang Bo, Li Tao, Liao Shixiu

Abstract excerpt

OBJECTIVE: To explore the effect of MTHFR and MTRR genes polymorphisms on chromosomes 18 and 21 non-disjunction through investigation of Henan Han Chinese young females with a gestational history of trisomy 21 (Down syndrome, DS) or trisomy 18 (Edwards syndrome, ES). METHODS: Polymorphisms of MTHFR 677C/T, MTHFR 1298A/C and MTRR 66A/G were analyzed in 73 healthy females (controls group), 78 females with a...

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Identifiers

PMID: 26037359
DOI: 10.3760/cma.j.issn.1003-9406.2015.03.021

Genes

MTHFR
MTRR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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