Article
Non-disjunction of chromosome 21, alphoid DNA variation, and sociogenetic features of Down syndrome.
TSitologiia i genetika - 1 Jan 2000
Vorsanova S G, Iourov I Y, Beresheva A K, Demidova I A, Monakhov V V, Kravets V S, Bartseva O B, Goyko E A, Soloviev I V, Yurov Y B
Abstract excerpt
The analysis of non-disjunction of chromosome 21 and alphoid DNA variation by using cytogenetic and molecular cytogenetic techniques (quantitative fluorescence in situ hybridization) in 74 nuclear families was performed. The establishment of possible correlation between alphoid DNA variation, parental age, environmental effects, and non-disjunction of chromosome 21 was made. The efficiency of techniques applied...
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