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Article

Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.

The EMBO journal - 1 May 1994

Metzler M, Gertz A, Sarkar M, Schachter H, Schrader J W, Marth J D

Abstract excerpt

Complex asparagine (N)-linked oligosaccharides appear late in phylogeny and are highly regulated in vertebrates. Variations in these structures are found on the majority of cell-surface and secreted proteins. Complex N-linked oligosaccharide biosynthesis is initiated in the Golgi apparatus by the action of Mgat-1-encoded UDP-N-acetylglucosamine:alpha-3-D- mannoside beta-1,2-N-acetylglucosaminyltransferase I...

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Identifiers

PMID: 8187759
DOI: 10.1002/j.1460-2075.1994.tb06480.x
PMCID: PMC395055

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