Article
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.
The EMBO journal - 1 May 1994
Metzler M, Gertz A, Sarkar M, Schachter H, Schrader J W, Marth J D
Abstract excerpt
Complex asparagine (N)-linked oligosaccharides appear late in phylogeny and are highly regulated in vertebrates. Variations in these structures are found on the majority of cell-surface and secreted proteins. Complex N-linked oligosaccharide biosynthesis is initiated in the Golgi apparatus by the...
Topics
- Animals
- Asparagine
- Base Sequence
- Carbohydrate Sequence
- DNA
- Embryo, Mammalian
- Embryonic Development
- Female
- Fetal Growth Retardation
- Genes, Lethal
- Hematopoiesis
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Molecular Sequence Data
- Morphogenesis
- Mutagenesis
- N-Acetylglucosaminyltransferases