Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA response.

doi:10.1111/j.1365-2249.1994.tb06567.x

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Article

Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA response.

Clinical and experimental immunology - 1 May 1994

Lue C, van den Wall Bake A W, Prince S J, Julian B A, Tseng M L, Radl J, Elson C O, Mestecky J

Abstract excerpt

Five patients on continuous ambulatory peritoneal dialysis (CAPD) were immunized intraperitoneally with tetanus toxoid (TT) through an indwelling catheter. Four control patients on CAPD received the same dose of TT intramuscularly. Before immunization, virtually no anti-TT antibody-secreting cell...

Topics

Adult
Antibodies
Antibody-Producing Cells
Ascitic Fluid
Black People
Cytoplasm
Female
Humans
Immunoglobulin A
Immunoglobulin G
Immunoglobulin Isotypes
Infusions, Parenteral
Male
Middle Aged

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peritoneal Dialysis, Continuous Ambulatory

Peritoneum

Phenotype

Safety

Source

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Identifiers

PMID: 8187345
DOI: 10.1111/j.1365-2249.1994.tb06567.x
PMCID: PMC1534882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8187345-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.