Article
Use of adenoviruses encoding CD40L or IL-2 against B cell lymphoma.
International journal of cancer - 10 Oct 2004
Meziane El Kahina, Bhattacharyya Tapan, Armstrong Anne C, Qian Cheng, Hawkins Robert E, Stern Peter L, Dermime Said
Abstract excerpt
Some B cell lymphomas lack important costimulatory properties that could prevent them from being used as cell based vaccines. Infection of A20 B lymphoma cells with a replication-defective adenovirus encoding murine (m) CD40L, but not mIL-2, produces an antigen presentation phenotype with upregulation of MHC Class I/II, induction of B7-1/2 molecules and production of MIL-12 and MIP-1alpha. Subcutaneous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
