Article
A two-component system that regulates an osmosensing MAP kinase cascade in yeast.
Nature - 19 May 1994
Maeda T, Wurgler-Murphy S M, Saito H
Abstract excerpt
In the prokaryotic two-component signal transduction systems, recognition of an environmental stimulus by a sensor molecule results in the activation of its histidine kinase domain and phosphorylation of a histidine residue within that domain. This phosphate group is then transferred to an aspartate residue in the receiver domain of a cognate response regulator molecule, resulting in the activation of its output...
Topics
- Amino Acid Sequence
- Fungal Proteins
- Histidine Kinase
- Intracellular Signaling Peptides and Proteins
- Molecular Sequence Data
- Mutation
- Phosphoprotein Phosphatases
- Phosphorylation
- Protein Kinases
- Protein Phosphatase 2
- Protein Phosphatase 2C