Article
A two-component system that regulates an osmosensing MAP kinase cascade in yeast.
Nature - 19 May 1994
Maeda T, Wurgler-Murphy S M, Saito H
Abstract excerpt
In the prokaryotic two-component signal transduction systems, recognition of an environmental stimulus by a sensor molecule results in the activation of its histidine kinase domain and phosphorylation of a histidine residue within that domain. This phosphate group is then transferred to an aspartate residue in the receiver domain of a cognate response regulator molecule, resulting in the activation of its output...
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