Article
Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1.
American journal of medical genetics - 15 Mar 1994
Pulver A E, Karayiorgou M, Wolyniec P S, Lasseter V K, Kasch L, Nestadt G, Antonarakis S, Housman D, Kazazian H H, Meyers D
Abstract excerpt
To identify genes responsible for the susceptibility for schizophrenia, and to test the hypothesis that schizophrenia is etiologically heterogeneous, we have studied 39 multiplex families from a systematic sample of schizophrenic patients. Using a complex autosomal dominant model, which considers only those with a diagnosis of schizophrenia or schizoaffective disorder as affected, a random search of the genome...
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