Article
Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1.
American journal of medical genetics - 15 Mar 1994
Pulver A E, Karayiorgou M, Wolyniec P S, Lasseter V K, Kasch L, Nestadt G, Antonarakis S, Housman D, Kazazian H H, Meyers D
Abstract excerpt
To identify genes responsible for the susceptibility for schizophrenia, and to test the hypothesis that schizophrenia is etiologically heterogeneous, we have studied 39 multiplex families from a systematic sample of schizophrenic patients. Using a complex autosomal dominant model, which considers...
Topics
- Adult
- Chromosomes, Human, Pair 22
- Female
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Lod Score
- Male
- Models, Genetic