Article
Evidence for a hypothetical non-HLA susceptibility gene in rheumatoid arthritis.
British journal of rheumatology - 1 May 1994
Pritchard M H
Abstract excerpt
In this study investigating possible reasons for the increased female prevalence of RA, family histories were obtained from 719 patients with classical RA by direct interview. Thirty-one per cent positively identified at least one affected relative. Compared with the expected population sex distribution ratio of 3:1 and local prevalence data, mothers with RA were eight times more common than predicted and fathers...
Topics
- Adult
- Arthritis, Rheumatoid
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DR Antigens
- Humans
- Male
- Sex Factors