Article
Differences between female and male patients with familial rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Apr 2001
Laivoranta-Nyman S, Luukkainen R, Hakala M, Hannonen P, Möttönen T, Yli-Kerttula U, Ilonen J, Toivanen A
Abstract excerpt
OBJECTIVE: To determine whether there are genetic differences between female and male patients with familial rheumatoid arthritis (RA). METHODS: 45 men and 119 women from 78 families with RA who all had at least one first degree relative with RA were compared. HLA-DRB1 alleles were analysed, including DRB1*04 subtypes and associations of DRB1*04 haplotypes with DQB1*0301 or DQB1*0302 alleles, the age of the...
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