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Article

Characterization of mutations that inactivate the diphtheria toxin repressor gene (dtxR).

Infection and immunity - 1 May 1994

Wang Z, Schmitt M P, Holmes R K

Abstract excerpt

The diphtheria toxin repressor (DtxR) is an iron-dependent regulator of diphtheria toxin production and iron uptake in Corynebacterium diphtheriae. It is activated in vitro by divalent metal ions including Fe2+, Cd2+, Co2+, Mn2+, Ni2+, and Zn2+. We characterized 20 different mutations in dtxR induced by bisulfite mutagenesis, 18 of which caused single-amino-acid substitutions in DtxR and two of which were...

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Identifiers

PMID: 8168920
DOI: 10.1128/iai.62.5.1600-1608.1994
PMCID: PMC186363

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Characterization of mutations that inactivate the diphtheria toxin repressor gene (dtxR).PMID 8168920Read ↗

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Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.Semantic proximity Read ↗

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