Article
Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Boyd J, Oza M N, Murphy J R
Abstract excerpt
Although the structural gene for diphtheria toxin, tox, is carried by a family of closely related corynebacteriophages, the regulation of tox expression is controlled, to a large extent, by its bacterial host Corynebacterium diphtheriae. Optimal yields of tox gene products are obtained only when...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Corynebacterium diphtheriae
- DNA, Bacterial
- Diphtheria Toxin
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genotype
- Iron
- Molecular Sequence Data
- Plasmids
- Promoter Regions, Genetic
- Restriction Mapping