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Article

Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990

Boyd J, Oza M N, Murphy J R

Abstract excerpt

Although the structural gene for diphtheria toxin, tox, is carried by a family of closely related corynebacteriophages, the regulation of tox expression is controlled, to a large extent, by its bacterial host Corynebacterium diphtheriae. Optimal yields of tox gene products are obtained only when iron becomes the growth-rate-limiting substrate. Previous studies suggest that regulation of tox expression is mediated...

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Identifiers

PMID: 2116013
DOI: 10.1073/pnas.87.15.5968
PMCID: PMC54451

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Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.PMID 2116013Read ↗

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