Article
New diphtheria toxin repressor types depicted in a Romanian collection of Corynebacterium diphtheriae isolates.
Journal of basic microbiology - 1 Oct 2014
Dinu Sorin, Damian Maria, Badell Edgar, Dragomirescu Cristiana Cerasella, Guiso Nicole
Abstract excerpt
Corynebacterium diphtheriae is the etiological agent of diphtheria, a potential fatal disease caused by a corynephage toxin. The expression of this diphtheria toxin is controlled via an iron-dependent repressor with various functions (DtxR). Some mutations in the dtxR gene are associated with diminished activity or even with total loss of DtxR function. We conducted a molecular study to characterize the dtxR...
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